Oncobites | Abstracts ESMO BREAST 26

ESMO BREAST 2026

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Efficacy of inavolisib (INAVO) + palbociclib (PALBO) +

fulvestrant (FULV) in patients (pts) with PIK3CA-mutated,

hormone receptor-positive, HER2-negative (HER2-),

endocrine-resistant advanced breast cancer (aBC) with and

without hyperglycaemia (HG) in the Phase III INAVO120 trial

420RO

Emergence of ESR1 mutations (ESR1m) in ctDNA during

first-line (1L) endocrine-based therapy in HR+/HER2_

advanced breast cancer: Findings from the SERENA-6

trial

419RO

Capivasertib (C) and fulvestrant (F) for patients (pts) with

HR+/HER2_ advanced breast cancer (ABC): final overall

survival (OS) results from the Phase 3 CAPItello-291 trial

417O

A window-of-opportunity (WOO) trial of giredestrant +/-

LHRH analogue vs anastrozole + LHRHa in

premenopausal patients with ER+/HER2- early breast

cancer: PREcoopERA

LBA2

ctDNA detection rates during surveillance in high-risk

HR+/HER2 negative breast cancer from the TRAK-ER study

1O